vignette: https://bioconductor.org/packages/release/bioc/vignettes/DESeq2/inst/doc/DESeq2.html
Input data:
key point:
- interger matrix
- un-normalized count: fit DESeq2 statistical model
- can take RNA-seq counts as well as ChIP-seq feature counts
vignette: https://bioconductor.org/packages/release/bioc/vignettes/DESeq2/inst/doc/DESeq2.html